Overzicht wetenschappelijk onderzoek


Het uitvoeren van wetenschappelijk onderzoek is één van de kerntaken van ZGT. Door wetenschappelijk onderzoek kunnen expertisegebieden ontwikkeld worden, wordt patiëntenzorg kwalitatief beter, kan bijgedragen worden aan nieuwe richtlijnen en standaarden en wordt naamsbekendheid opgebouwd. De diabetische voetenpoli is een van de topklinische zorggebieden van ZGT en is verantwoordelijk voor een groot deel van de wetenschappelijke publicaties vanuit ZGT. Hieronder vind u een overzicht van promovendi de lopende studie en publicaties.

Gebruik de links om meer te weten te komen.

Lopende onderzoeken

Binnen de onderstaande onderzoekslijnen zijn er ook mogelijkheden voor stages. Je kan mailen naar k.kappert””at””zgt.nl voor meer informatie.

  • PRESERVE study
  • FoRever: follow-up after revascularization using Laser Speckle Contrast Imaging
  • Clinical outcomes of the Modified In Situ Reverse Arterialization using new imaging techniques
  • 3D printing for offloading the diabetic feet
  • The badmat project: An 360 degree early foot ulcer detection system for home use
  • 3D-planning in complex foot surgery
  • Clinical outcomes of charcot foot surgery
  • Perioperative plantar pressure measurements of Charcot foot.

Promovendi

Kor Hutting –
Afram Akturk –
Manon Westra – Factoren van ontlastende behandelingsmethodes om de plantaire druk in de diabetische voet te verlagen.

Proefschriften

Wouter aan de Stegge – Prevention and prediction of foot ulcer recurrence in diabetes (2022)
Onno Mennes –  Laser Speckle Contrast Imaging for assessing microcirculation in diabetic foot disease (2022)
Rob van Doremalen – The unattained power of the third dimension in medical imaging: Implications for clinical practice (2021)
Chanjuan Liu – An Intelligent Telemedicine System for Detection of Diabetic Foot Complications (2014)

Recente publicaties:

The Association between Foot and Ulcer Microcirculation Measured with Laser Speckle Contrast Imaging and Healing of Diabetic Foot Ulcers.
Mennes OA, van Netten JJ, van Baal JG, Slart RHJA, Steenbergen W.
J Clin Med. 2021 Aug 27;10(17):3844. doi: 10.3390/jcm10173844.
PMID: 34501291

Effectiveness of at-home skin temperature monitoring in reducing the incidence of foot ulcer recurrence in people with diabetes: a multicenter randomized controlled trial (DIATEMP).
Bus SA, Aan de Stegge WB, van Baal JG, Busch-Westbroek TE, Nollet F, van Netten JJ.
BMJ Open Diabetes Res Care. 2021 Sep;9(1):e002392. doi: 10.1136/bmjdrc-2021-002392.
PMID: 34493496 Free PMC article. Clinical Trial.

Development of a prediction model for foot ulcer recurrence in people with diabetes using easy-to-obtain clinical variables.
Aan de Stegge WB, Schut MC, Abu-Hanna A, van Baal JG, van Netten JJ, Bus SA.
BMJ Open Diabetes Res Care. 2021 Jul;9(1):e002257. doi: 10.1136/bmjdrc-2021-002257.
PMID: 34301678 Free PMC article.

Improved outcomes in patients with diabetic foot ulcers despite of differences in baseline characteristics.
Akturk A, van Netten JJ, Vermeer M, Kruse RR, Schaper NC, van Gemert-Pijnen LJEWC, van Baal JG.
Wound Repair Regen. 2021 Nov;29(6):912-919. doi: 10.1111/wrr.12976. Epub 2021 Oct 19.
PMID: 34665904

Surgical Treatment of Diabetic Foot Ulcers Complicated by Osteomyelitis with Gentamicin-Loaded Calcium Sulphate-Hydroxyapatite Biocomposite.
Hutting KH, Aan de Stegge WB, van Netten JJ, Ten Cate WA, Smeets L, Welten GMJM, Scharn DM, de Vries JPM, van Baal JG.
J Clin Med. 2021 Jan 19;10(2):371. doi: 10.3390/jcm10020371.
PMID: 33478085

Infrared thermography for monitoring severity and treatment of diabetic foot infections.
Hutting KH, Aan de Stegge WB, Kruse RR, van Baal JG, Bus SA, van Netten JJ.
Vasc Biol. 2020 Jul 21;2(1):1-10. doi: 10.1530/VB-20-0003. eCollection 2020.
PMID: 32935076

Semi-Automatic Tracking of Laser Speckle Contrast Images of Microcirculation in Diabetic Foot Ulcers.
Mennes OA, Selles M, van Netten JJ, van Baal JG, Steenbergen W, Slart RHJA.
Diagnostics (Basel). 2020 Dec 6;10(12):1054. doi: 10.3390/diagnostics10121054.
PMID: 33291254

Infrared 3D Thermography for Inflammation Detection in Diabetic Foot Disease: A Proof of Concept.
van Doremalen RFM, van Netten JJ, van Baal JG, Vollenbroek-Hutten MMR,
van der Heijden F.
J Diabetes Sci Technol. 2020 Jan;14(1):46-54. doi: 10.1177/1932296819854062. Epub 2019 Jun 14.
PMID: 31200612

Assessment of microcirculation in the diabetic foot with laser speckle contrast imaging.
Mennes OA, van Netten JJ, van Baal JG, Steenbergen W.
Physiol Meas. 2019 Jul 1;40(6):065002. doi: 10.1088/1361-6579/ab2058.
PMID: 31071696

Validation of low-cost smartphone-based thermal camera for diabetic foot assessment.
van Doremalen RFM, van Netten JJ, van Baal JG, Vollenbroek-Hutten MMR, van der Heijden F.
Diabetes Res Clin Pract. 2019 Mar;149:132-139. doi: 10.1016/j.diabres.2019.01.032. Epub 2019 Feb 6.
PMID: 30738090

Ulcer-free survival days and ulcer healing in patients with diabetic foot ulcers: A prospective cohort study.
Akturk A, van Netten JJ, Scheer R, Vermeer M, van Baal JG.
Int Wound J. 2019 Dec;16(6):1365-1372. doi: 10.1111/iwj.13199. Epub 2019 Aug 19.
PMID: 31429183

Effect of different casting design characteristics on offloading the diabetic foot.
Westra M, van Netten JJ, Manning HA, van Baal JG, Bus SA.
Gait Posture. 2018 Jul;64:90-94. doi: 10.1016/j.gaitpost.2018.05.022. Epub 2018 May 22.
PMID: 29890399 Clinical Trial.

An exploratory study on differences in cumulative plantar tissue stress between healing and non-healing plantar neuropathic diabetic foot ulcers.
van Netten JJ, van Baal JG, Bril A, Wissink M, Bus SA.
Clin Biomech (Bristol, Avon). 2018 Mar;53:86-92. doi: 10.1016/j.clinbiomech.2018.02.012. Epub 2018 Feb 19.
PMID: 29477099 Clinical Trial.

The cost-effectiveness and cost-utility of at-home infrared temperature monitoring in reducing the incidence of foot ulcer recurrence in patients with diabetes (DIATEMP): study protocol for a randomized controlled trial.
Aan de Stegge WB, Mejaiti N, van Netten JJ, Dijkgraaf MGW, van Baal JG, Busch-Westbroek TE, Bus SA.
Trials. 2018 Sep 24;19(1):520. doi: 10.1186/s13063-018-2890-2.
PMID: 30249296

The efficacy of removable devices to offload and heal neuropathic plantar forefoot ulcers in people with diabetes: a single-blinded multicentre randomised controlled trial.
Bus SA, van Netten JJ, Kottink AI, Manning EA, Spraul M, Woittiez AJ, van Baal JG.
Int Wound J. 2018 Feb;15(1):65-74. doi: 10.1111/iwj.12835. Epub 2017 Oct 23.
PMID: 29057609 Clinical Trial.

Collateral artery pathways of the femoral and popliteal artery.
Kruse RR, Doomernik DE, Maltha KV, Kooloos JGM, Kozicz TL, Reijnen MMPJ.
J Surg Res. 2017 May 1;211:45-52. doi: 10.1016/j.jss.2016.11.068. Epub 2016 Dec 14.
PMID: 28501130

A multidisciplinary approach in diabetic foot disease is mandatory.
van Baal JG, Aan de Stegge WB, Schaper NC.
Ned Tijdschr Geneeskd. 2017;161:D1755.
PMID: 29057728 Review. Dutch.